Ensure TwoCal is a nutritionally complete, high energy, high protein nutritional drink, designed for people with involuntary weight loss, those who are recovering from illness or surgery or those who have increased nutritional needs. Ensure Two Cal Neutral is the high energy and protein nutritional supplement drink. It is specifically designed for people with involuntary weight loss and those who are recovering from illness or require extra nutrients or sugar. It is free from l e & gluten and can be used as a supplement to meals or even as a snack.