Kleenex Extra Large Compact Tissues are the same big tissues for even the most delicate of noses, but in a new smaller box. Kleenex Extra Large Compact Tissues: Just as big. Just as strong, but now available in a smaller box. About The Kleenex Brand Kleenex facial tissue was first introduced in 1924, when a package of 100 sheets sold for 65 cents. Although it was originally marketed as a cold cream remover, people used the tissue many other ways, especially as a disposable handkerchief. In 1930, advertising was changed to reflect this usage, and today more people buy Kleenex facial tissue than any other brand. Kleenex facial tissue celebrated its 75th anniversary in 1999. By promoting it as a cleaner, healthier alternative to towels and handkerchiefs it quickly became a mainstay in households across the nation.