When Mr and Mrs Little (Hugh Laurie and Geena Davis) visit an orphanage to find a brother for their son George (Jonathan Lipnicki) they come away with a charming talking mouse called Stuart. After initial misgivings, George and Stuart begin to get on famously, and everything seems to be going perfectly; but unknown to the family, the neighbourhood cats have ganged together with the sole intention of getting rid of Stuart. Co-written by M. Night Shyamalan (\'The Sixth Sense\') and featuring state-of-the-art computer-generated effects and Michael J. Fox as the voice of Stuart.