What is Cuticura Mildly Medicated Talcum Powder? The Mildly Medicated Talcum Powder from Cuticura has been specially formulated to be effective for combating the symptoms of eczema-prone, irritated and dry skin.  How to Apply Cuticura Mildly Medicated Talcum Powder The Mildly Medicated Talcum Powder can be used as a once or twice a day treatment.  For best results, dry your skin thoroughly before applying. Apply a small amount of Mildly Medicated powder onto the palm of your hands and gently smooth onto the area of concern or irritation. Always Read Full Instructions/Patient Information Leaflet Before Use