Imbalanced micro-flora populations can alter the nutrient status, immune response, or detoxification capacity of the host, interfering with overall health. This Berberine & Grapefruit Seed formula has been specifically designed to support a healthy intestinal environment. All of the herbs in the formula have been shown to help maintain a balance of micro-flora in the gastrointestinal tract. Gentian contains very bitter compounds (gentiopicrin and amarogentin) that support normal digestive function. Garlic contains allicin, a sulphur compound, which may also help to establish microbial balance.Ingredients: One tablet of Nutri Berberine & Grapefruit Seed contains: Berberine sulphate 100 mg Grapefruit seed extract (Citrus paradisi) 100 mg Gentian Root Extract (Gentiana lutea) 75 mg 4:1 concentrate Goldenseal root extract (Hydrastis canadensis) 50 mg (5% Hydrastine) Sweet Annie Aerial Parts (Artemesia annua) 50 mg Quassia Bark Extract (Picrasma excelsa) 50 mg 4:1 concentrate Black Walnut, Green Hull extract (Juglans nigra) 50 mg 4:1 concentrate Garlic Bulb extract (Allium sativum) 0.8% Allicin 50 mg Other Ingredients:Magnesium stearate, Microcrystalline cellulose, Natural polysaccharide capsule (UltraCapsâ„¢), Silicon dioxide.Directions: Take 2-4 capsules daily or as directed. Alternatively follow this commonly used program: Month 1: 2-4 capsules, three times daily, every other day. Month 2: 2-4 capsules, three times daily, twice a week. Month 3: 2-4 capsules three times daily, once a week. Caution: Not recommended during pregnancy or breast-feeding. Only use in children under age 12 with medical supervision.