Sinus Rinse Refills are premixed sachets of USP grade Sodium Chloride and Sodium Bicarbonate. A large volume low pressure nasal wash is the most effective way to irrigate the nose based on current medical studies. Nasal irrigation is an excellent way to cleanse mucus from the nose making medications more effective. They also clean allergens, irritants, bacteria, and viruses from the nose reducing the frequency of infection. Furthermore they help decrease swelling in the nose and increase air flow. Sinus Rinse is great for all ages; it is available in Isotonic, Paediatric and Hyper-tonic concentrations. Key Features:1. Full 60 day supply if using twice a day as recommended 2. Premixed sachets 3. pH balanced, no burning, no stinging 4. USP grade solution(99% purity)