Spedra tablets contain the active ingredient avanafil which belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. Spedra is a treatment for adult men suffering from erectile dysfunction much like Viagra and Sildenafil.  Spedra works by helping the blood vessels in your penis to relax. This increases the blood flow into your penis, helping it stay hard and erect when you get sexually excited. Spedra is known to be fast acting and can start working within 15 minutes of taking a tablet.