Meet the Sais, a Nigerian-Ghanaian family living in the United States. A family prospering until the day father and surgeon Kweku Sai is victim of a grave injustice. Ashamed, he abandons his beautiful wife Fola and their little boys and girls, causing the family to fracture and spiral out into the world - New York, London, West Africa, New England - on uncertain, troubled journeys until, many years later, tragedy unites them. Now this broken family has a chance to heal - but can the Sais take it?