RRP £160 - Prevents and corrects the most visible signs of aging - helps alleviate the discomfort associated with dry,dehydrated and aging skin - suitable for crepey, thin, wrinkled and sun damaged skin.PREVENT & CORRECT SkinCeuticals A.G.E. Interrupter A.G.E. Interrupter is specifically formulated to improve the creping, thinning appearance of mature skin caused by intrinsic or internal aging processes such as glycation. Intrinsic aging, caused by internal factors such as hormonal shifts and metabolic slowdown, contributes greatly to skin sagging, creping, thinning, and cracking. A.G.E. Interrupter is a unique treatment formulated with 4% blueberry extract, 30% Proxylane™, and 0.2% phytosphingosine to help prevent the glycation process and correct severe signs of intrinsic aging in mature skin. Blueberry extract is both an antioxidant and anti-glycation ingredient that inhibits advanced glycation end-products (A.G.E.) while preventing further oxidation from ccurring. Proxylane™ rebuilds the support structure that degrades as a direct result of intrinsic aging and efficiently improves anchorage of the skin’s upper layers onto the dermis to increase elasticity and thickness. Phytosphingosine protects the skin’s barrier, while rich emollients hydrate dry, cracking skin. This multi-faceted and uniquely-textured formulation is optimized to prevent and correct the most visible signs of aging, while minimizing the associated discomfort and dryness.Size: 48ml Benefits:4% Blueberry Extract- Slows down the process of A.G.E. formation, preventing the rigidification of collagen and elastin fibers - Normalizes MMP-1 to help protect non-glycated collagen types IV and VII from erosion - Exhibits a pro-matrix effect – stimulating synthesis of procollagen I and III 30% concentration of Proxylane - the concentration proven to be effective in published studies- Stimulates glycosaminoglycan (GAG) synthesis, to remodel tissue structure in the dermal epidermal junction (D.E.J.) and increase elasticity and thickness — as if the skin’s mattress has been re-inflated from the inside - Increases collagen IV and VII gene expression - Improves dermal-epidermal anchorage - Increases CD44, a hyaluronic acid receptor, to increase bound moisture in the epidermis 0.2% Phytoshingosine- Reinforces the skin’s barrier by increasing the synthesis of enzymatic and cellular components - Synthesizes lipids necessary for barrier function (ceramides, cholesterol) - Increases the level of filaggrin, the precursor of the natural moisturizing factor (NMF) to enhance the natural moisture barrier Rich, moisturizing base - Hydrates dry, cracking skin - Helps alleviate the discomfort associated with dry, aging skin Directions:Recommened for Mature/post-menopausal skin,Age-related moisture loss Dry, dull or delicate skin crepey, thin, and wrinkled skin 50+Apply in place of a moisturiser once or twice a day to entire face and neck.