Fillerina Lips and Mouth Grade 5 has been formulated in 2 different increasing concentrations to be chosen according to the individual needs. Lip and Mouth Grade 5 is a replenishing gel containing 8 Hyaluronic Acids and 3 Collagens that plump the lips and fill in the lines around the mouth. Grade 4 targets lips with marked emptying, very irregular texture and marked wrinkles on the mouth contour. How to choose your grade with Fillerina: - Grade 1 has a higher concentration of larger molecules for plumping and hydration. - Grade 2 has a perfect blend of all size molecules. - Grade 3 has a higher concentration of smaller molecules, which are needed to travel to the deeper layers of the skin for filling moderate wrinkles. - Grade 4 & 5 have larger amounts of NEW smaller molecules to penetrate to the deepest layers of the skin for the filling of deep to very deep expression lines and loss of volume. Recommended for very mature skin.