Aspirin 300mg Tablets relieve pain, swelling and high temperature, making them great for treating headaches, migraine, neuralgia, toothache, sore throat, period pains and for the relief of sprains, strains, rheumatic pain, sciatica, lumbago, muscle aches, fibrositis, joint swelling and stiffness. They can also be used to relieve the symptoms of flu and feverish colds. Aspirin belongs to a group of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) and works as a pain reliever, antipyretic (which means that it reduces temperature) and anti-inflammatory.