Dulcolax Twelve Plus Pico Liquid is used for the short-term relief of occasional constipation. **Key Benefits:** - Fruit flavoured liquid - 300ml Suspension - 5mg of Sodium Picosulfate per 5ml dose - Sugar Free - Works in 6-12 hours - Stimulant laxative Ducolax Twelve Plus Pico Liquid is a fruit flavoured liquid for overnight relief from constipation. By stimulating both the colon and the rectum it may also help the bowel to return to normal regular function. Dulcolax Twelve Plus Pico Liquid Oral Solution is recommended to be taken at night to produce evacuation the following morning. What is constipation? Normal and regular bowel movement is important for most people. However, what is \"normal and regular\" varies from person to person. Some may have a bowel movement every day, others less often. Whatever it is like for you, it is best that your bowel movement has a regular pattern. Constipation is an occasional problem for some people. For others, it may more often. It happens when the normal muscle actions in the bowel (large intestine) slow down. This can mean that material is not easily eliminated from the body. The cause of constipation is often not known. It can be associated with: Sudden change of diet, loss of \"tone\" of the bowel muscles in older people, pregnancy, medicines such as Morphine or Codeine, having to stay in bed for a long time and lack of exercise. These healthy tips are recommended to try to prevent constipation happening: Eat a balanced diet including fresh fruit and vegetables, drink enough water so that you do not become dehydrated, keep up your exercise and stay fit and make time to empty your bowels when your body tells you.