A high potency active B12 supplement containing 500µg of methylcobalamin and 500µg adenosylcobalamin, which are both active forms of this important vitamin. - Sublingual means beneath the tongue and these tablets will dissolve in the mouth allowing oral absorption - Methylcobalamin is the active form used in the methylation cycle. Methylation reactions occur in every cell in the body – there are more than a billion per second - Adenosylcobalamin is the active form that is used in the mitochondria (which are the energy power houses of cells) - Vegan and vegetarian diets can be low in B12 - Other people at risk of low B12 include those with digestive conditions that lead to malabsorption; low stomach acid (e.g. due to long-term antacid medication, proton pump inhibitors, H2 blockers, ageing or zinc deficiency); surgery where nitrous oxide has been used as an anaesthetic; and other prescription medications which impair B12 absorption (e.g. metformin, colchicine, neomycin and others) Vitamin B12 contributes to normal: - energy-yielding metabolism - functioning of the nervous system - homocysteine metabolism - psychological function - red blood cell formation - immune system function Vitamin B12 contributes to the reduction of tiredness and fatigue Vitamin B12 has a role in the process of cell division