ESI Aloe Fresh Sensitive Sustained Protection Gel Toothpaste contains active ingredients including Aloe Vera, Birch, Chitosan, Tea Tree and Silica. This toothpaste is designed to protect teeth from dental plaque while supporting gum health without the use of fluoride and artificial ingredients. This formulation is designed to protect sensitive teeth between brushing. Aloe Vera is native to Africa, but is grown today in the West Indies and the American Southwest. Aloe is a member of the lily family, although it resembles cactus. It has been used since ancient times, but only recently has it enjoyed a rediscovery and subsequent popularity explosion. Due to increased demand, many companies manufacture aloe vera. Unfortunately, many of these products lose much of the plants original benefits by over processing. Some claim to have removed the disagreeable taste of the plant´s juice, for example. But in doing so, they end up with a product that is only 10-15% aloe vera, at best. The Aloe Vera which goes into the ESI Aloe Fresh Sensitive Gel Toothpaste is processed in a special way to avoid the loss of essential vitamins, minerals, and other active constituents. The leaf is filleted; then the green outer portion that contains aloin is removed, leaving the gel that remains in the leaf. The gel remains thick when the leaf is first cut, but after a few minutes, an enzymatic reaction causes it to become liquid and freely run out. It is this 100% pure liquid that our manufacturer collects.