Joint & Cartilage Precursors. High Level Evidence for Glucosamine. 1500 mg Glucosamine Sulfate. Clinically Relevant Quantities of Both. Glucosamine (1.5 g) & Chondroitin (1.2 g). Glucosamine + Chondroitin + MSM provides efficacious quantities of glucosamine sulfate, chondroitin sulfate, and MSM combined with vitamin C and manganese for optimizing joint health. Glucosamine and chondroitin sulfate are fundamental components of joint tissue involved in the production of hyaluronic acid, which is an important component of the synovial fluid that lubricates the joints and a major component of the connective tissue in the skin. Methylsulfonylmethane (MSM) is an organic source of sulfur, an antioxidant mineral and critical component of structural body tissues, such as cartilage. The sulfur from MSM is incorporated into joint tissues as glycosaminoglycans (or mucopolysaccharides) such as chondroitin sulfate and hyaluronic acid. Vitamin C and manganese are required for the synthesis of collagen and cartilage. Jarrow Formulas Glucosamine + Chondroitin + MSM is Joint Sustain nutrition, providing a SODIUM FREE form of glucosamine sulfate stabilized with only potassium chloride (KCl).Gluten free, Dairy free, Egg free. Contains shellfish.