The Beaphar CatComfort Calming Spot-On is a simple and effective solution to reducing problem behaviour in cats, such as excessive meowing, aggressive behaviour, fighting, avoidance, hiding or general feelings of anxiety. It is beneficial when cats are faced with new experiences, such as multi-cat households, social situations, a new family and learning periods. The Beaphar CatComfort Calming Spot-On contains a copy of the naturally produced Maternal Appeasing Pheromone, which is instantly recognisable to cats. It is naturally produced by the queen when she nurses her kittens, and is a crucial part of the bonding process. By using a copy of this pheromone in the Beaphar CatComfort Calming Spot-On, it gives a continuous and reassuring message to help cats feel at ease wherever they are. As cats are naturally solitary, this can be particularly valuable in multi-cat households, helping to promote harmonious living. Once applied, the spot-on works quickly and will start creating a calming effect after around 15 minutes. This easy-to-use spot-on provides a long-lasting calming effect for up to one week. Simply apply to the top of your cat?s head and the pheromones will diffuse into the air creating a calming effect, helping them feel safe and reassured. It is ideal for helping to facilitate bonding between cats or with other members of the family. The spot-on must be applied at least 15 minutes before a potentially stressful situation. Suitable for all breeds of cat. ALWAYS FULLY READ THE PRODUCT LABEL AND PACKAGING BEFORE USE. The spot-on must be applied at least 15 minutes before a potentially stressful situation. If your cat gets very wet, such as in heavy rain or following a bath, reapply the drops as the calming effect may be diminished. If you use a spot-on flea product, this is usually applied between the animal\'s shoulder blades. Take care to apply the Beaphar CatComfort Calming Spot-On in a different place to the flea product, ideally between the ears. If this is not possible it is advisable to leave 48 hours between applying the two products.