Urys CAPSULE Suitable for the protection of the urinary tract of the dog and cat. Useful to preserve the physiological reactivity of the urinary system, protecting it from damage itessuti inflammatory and oxidative. It provides the function of mucosavescico-urethral. Palmitoylethanolamide or PEA Aliamide able to check the response mast cell, lowering the tone didegranulazione and limiting, thus, the release of harmful factors (eg. NO), neurosensitizzanti (eg. NGF) and inflammatory (eg. TNF). On mast cells isolated from dog, countries pre-installed is shown to be active in reducing the release of histamine, TNF-alpha and PGD2 (prostaglandin D2). In an animal model of cystitis, PEA was able dinormalizzare the threshold of urination. Ultimately, the PEA rule reattivitadella mucosa vesicourethral. Glucosamine HCl (hydrochloride) Natural precursor of glycosaminoglycans (GAGs); has excellent oral absorption doposomministrazione. It stimulates GAG synthesis, and thus facilitates the riparazionedelle holes that have formed nell\'urotelio being LUTD. Hesperidin Flavonoid natural no side effects. Its active form (hesperetin) siconcentra in the urine, where it reduces the amount of bacteria and the stressossidativo. Ingredients to 1 capsule PEA-um (Palmitoylethanolamide ultra-micronized) 75mg Glucosamine HCI 100 mg Hesperidin 60 mg How to use 1 capsule per day per 10 kg of body weight. Format 30 capsules pin. Cod. 2064 Bibliography - Palmitoylethanolamide, endocannabinoids and analogs composticannabimimetici protection. Re G, Barbero R, Miolo A, Di Marzo V. - Oral administration of glucosamine in the treatment of idiopathic dellacistite cat. Gunn-Moore DA, Shenoy CM. - The administration of endocannabinoids previenel\'iperalgesia related, associated with inflammation. Farquhar-Smith PW, RiceASC. - Biochemistry and pharmacology of amides of fatty acids: effects on inflammation, pain. Di Marzo V. - The mast cell in interstitial cystitis: role infisiopatologia and pathogenesis. Sant GR, Kempuraj D, Marchand JE, Theoharides TC. - Immunohistochemical Determination of mast cells in the course of disindrome bladder pain. Larsen MS, Mortensen S, Nordling J, Horn T. - Control cannabimimetico of mast cell degranulation: New Perspectives in inflammation. De Filippis D, D\'Amico A, Iuvone T. - Palmitoylethanolamide, acilamide endogenous, has effettianti-allodinici and anti-hyperalgic. Costa B, Comelli F, Bettoni I, Colleoni MP, GiagnoniG. - The role of mast cells and the protease activated receptor (PAR-2). Wang ZY, Wang P, Bjorling DE. - Changing paradigms of idiopathic cystitis in cats. KrugerJM, CA Osborne, JP Lulich. - Mechanisms of disease: the role of NGF nellafisiopatologia of urinary disorders. Steers WD, Tuttle JB. - Assessment of the effects of stress in cats with idiopathic dacistite. Westropp JL, Kass PH, Buffington CAT.