Now available at Face the Future Advanced Skin Clinic and Online Shop, Jan Marini Age Intervention Retinol Plus provides unparalleled skin rejuvenation benefits. Retinol PLUS truly separates itself from the pack. The most aggressive levels of stabilized all-trans-retinol are synergistically combined with advanced topical agents to maximize efficacy while simultaneously decreasing or even eliminating acclimation/irritation concerns. Age Intervention Retinol PLUS is significantly more than a retinol product. Especially formulated to utilize the maximum amount of all-trans-retinol PLUS anti-aging and collagen boosting peptides, antioxidants, hydrators and skin soothing ingredients. Directions: For the first 1-2 weeks, apply product sparingly over entire face every other evening, then slowly increase usage, as tolerated, to 1-2 times daily. If irritation occurs, decrease the frequency of application to allow the skin greater time to acclimate. Size: 28 g